Biostable insect kinin analogs reduce blood meal and disrupt ecdysis in the blood-gorging Chagas’ disease vector, Rhodnius prolixus
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چکیده
منابع مشابه
Aspects of the control of diuresis in the blood gorging insect, Rhodnius prolixus
Post-feeding diuresis in Rhodnius prolixus is neurohormonally controlled by serotonin and at least one peptidergic diuretic hormone (possibly a CRF-related peptide). These appear to be released by two different neurosecretory groups – 5 dorsal unpaired median (DUM) cells and 5-6 lateral neurosecretory cells of the mesothoracic ganglionic mass. The DUM cells co-localize serotonin and the calcito...
متن کاملIsolation and characterization of a novel insect defensin from Rhodnius prolixus, a vector of Chagas disease.
An antimicrobial peptide belonging to the defensin family of small cationic peptides associated with innate immunity in insects was isolated from the hemolymph of Rhodnius prolixus, a vector of Chagas disease. This peptide, designated R. prolixus defensin A, was purified and sequenced. The active peptide contains 43 residues and aligns well with other insect defensins. However the pre-pro regio...
متن کامل[Blood-feeding of Rhodnius prolixus].
Triatomines (Hemiptera: Reduviidae) are blood-sucking insect vectors of the protozoan Trypanosoma cruzi which is the causative agent of Chagas' disease. Rhodnius prolixus is the most epidemiologically important vector of T. cruzi in Colombia. Triatomines are regarded to be vessel-feeders as they obtain their blood meals from vertebrate hosts by directly inserting their mouthparts into vessels. ...
متن کاملGenome of Rhodnius prolixus, an insect vector of Chagas disease, reveals unique adaptations to hematophagy and parasite infection.
Rhodnius prolixus not only has served as a model organism for the study of insect physiology, but also is a major vector of Chagas disease, an illness that affects approximately seven million people worldwide. We sequenced the genome of R. prolixus, generated assembled sequences covering 95% of the genome (∼ 702 Mb), including 15,456 putative protein-coding genes, and completed comprehensive ge...
متن کاملEvidence for a conserved CCAP-signaling pathway controlling ecdysis in a hemimetabolous insect, Rhodnius prolixus
A vital feature in the success of Ecdysozoa is their ability to shed their exoskeleton (a process called ecdysis) such that they can grow or change their morphology. In holometabolous insects, these behaviors are orchestrated by the sequential actions of neuropeptides, one of which is crustacean cardioactive peptide (CCAP). Little is known about the control of ecdysis in hemimetabolous insects....
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ژورنال
عنوان ژورنال: Peptides
سال: 2016
ISSN: 0196-9781
DOI: 10.1016/j.peptides.2016.01.012